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Secrets of the Hive
Propolis might have life-saving properties

By Sara Specht

Unexplained disappearances, a baffling plague, an irreplaceable society crumbling: these are not the trappings of a musty history textbook or war coverage from across an ocean. They are essential pieces of a modern-day mystery that spans the globe.

This is the story of honeybees, their struggle to survive and the secret they may have to saving themselves. It’s the tale of three CFANS investigators and their team, who hope to learn the bees’ secret and use it to save humans, as well.

And it all began with a sore throat.

Once upon a time
About seven years ago, a researcher from the Ukraine working at the University of Minnesota medical school on lab trials to combat HIV came down with a cold. She, like countless people around the world, had always relied on a traditional treatment for such woes, a substance found in any honeybee hive: propolis.

Propolis, sometimes known as bee glue, is a thick, sticky resin that bees collect from tree buds and use to cement holes in the hive and defend it against invading parasites and diseases. Traditional healers from South America to China, Japan to Eastern Europe, have valued propolis as a remedy for such ailments as gum problems and dental health, skin issues and oral sores, as well as viruses and the common cold.

 
 

The researcher tracked down propolis at the Minneapolis farmers’ market and made herself a tincture to soothe her viral woes. Then she brought her cure to work with her and ran a test: propolis versus HIV. Propolis won.

Propolis demonstrated antiviral activity against HIV, prompting a study on propolis that paired the medical school with a team of researchers from CFANS. That project showed promising results, but propolis is an incredibly complex substance, and the mystery of precisely which elements are active remained unsolved. The researchers involved, though, didn’t stop considering the study’s implications.

Where the bees are
“I started thinking, ‘wait, if propolis is so good for humans, it’s got to also be good for bees,’” explains Marla Spivak, co-principal investigator in a new two-year project to identify the active compounds in honeybee propolis.

Mike Wilson, Jerry Cohen, Gary Gardner and Lana Barkawi in their lab on campus.

Mike Wilson, Jerry Cohen, Gary Gardner and Lana Barkawi in their lab on campus.



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